Evolution of oxytocin pathways in the brain of vertebrates. Oxytocin and vasopressin: linking pituitary neuropeptides and their receptors to social neurocircuits. Harv Rev Psychiatry 2011 19:1–14.īaribeau DA, Anagnostou E. The role of oxytocin in mother-infant relations: a systematic review of human studies. Galbally M, Lewis AJ, IJzendoorn M van, Permezel M. Synthesis, transport, and release of posterior pituitary hormones. Based on evidence from these studies, we explore the potentials and limitations of oxytocin’s pharmacotherapeutic applications as a treatment to improve neuropsychological disorders.īrownstein MJ, Russell JT, Gainer H. Here, we intend to review various theories regarding the effect of oxytocin on memory, accompanied by its mechanisms which are proposed in human and animal experiments. Therefore, understanding the effects of oxytocin, within various emotional and social context, is important before oxytocin could be efficiently used for improving learning and communication impairment or managing neuropsychological disorders. The inconsistent evidence of general oxytocin effects on memory and neuropsychological conditions is an important issue in considering oxytocin as an adjunct therapy. The factors that lead to the effects of oxytocin and its underlying processes on such variables are still uncertain. However, recent studies also have shown that the effect of oxytocin could varied, even leading to reverse results. The ease of access to the brain intranasally, numerous positive evidences and widely advertised as a wonder drug, foster this interest. There is a growing interest in the use of oxytocin as a treatment for memory-related psychological disorders and social cognitive disorders. Studies have indicated that oxytocin has an influence on cognitive functions such as attention, memory and emotional regulation, particularly in the context of social and communicative behavior. Oxytocin, Memory, Contextual factor, Psychological disorders, Cognitive function Abstract Modeling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran. Laboratory of Neurosciences and Behavior, Department of Physiological Sciences, Institute of Biology, University of Brasilia, CEP 70910-900 Brasilia, DF, Brazil.Ħ. Institute of Neuroscience, The Center of Excellence in Brain and Intelligence Technology, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, Chinese Academy of Sciences, Shanghai, China.Ī:1:Ĥ.ğederal University of Pernambuco, Health Sciences Center, Department of Nutrition, LNED, Recife, PE, Brazil.ĥ. On the Possibility to Use Oxytocin as A Potential Therapeutic Approach for Memory-Related Psychological DisordersĢ.ĝepartment of Dana Brain Health Institute, Iranian Neuroscience Society-Fars Chapter, Shiraz, Iran and 1.
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